Who could tell me??????

I need to know how you get rid of say your pyzam layout to put in thecutestblogontheblock layout. everytime i go to put one of those darn cute layouts on, i could never get my pyzam layout off .................so my layout would look like this, the middle of the layout is pyzam with the text writing from pyzam and then the cutest blog on the block would be surrounding it. This is my problem!!!!! I need a blog 101 class to learn all the tricks of the trade of blogging. blogging party anyone?????? I need to help ..lol:) call me if you know how to fix my problem
Suz
801-916-7183